Bioactivity:

CC-223 is an orally available mTOR inhibitor with potential antitumor activity. CC-223 inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor cell proliferation. CC-223 is a potent mTOR kinase inhi

CAS nr:

1228013-30-6

Purity:

98%

Molecular Weight:

397,47

SMILES:

CO[C@H]1CC[C@@H](CC1)N1C(=O)CNc2ncc(nc12)-c1ccc(nc1)C(C)(C)O

Formula:

C21H27N5O3

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,PI3K/Akt/mTOR signaling,PI3K/Akt/mTOR signaling,PI3K/Akt/mTOR signaling,DNA Damage/DNA Repair,Apoptosis,Tyrosine Kinase/Adaptors

Target:

FLT,FLT,mTOR,PI3K,DNA-PK,DNA-PK,Apoptosis,c-Fms