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Bioactivity:
QNZ (EVP4593) is an effective inhibitor of NF-_B activation and TNF-_ production. The IC50 of QNZ for NF-_B and TNF-_ is11 nM and 7 nM, respectively.
CAS nr:
545380-34-5
Purity:
98%
Molecular Weight:
356,42
SMILES:
c1ccc(cc1)Oc1ccc(cc1)CCNc1ncnc2c1cc(cc2)N
Formula:
C22H20N4O
Pathway:
Apoptosis,NF-_b
Target:
TNF,NF-_B