Bioactivity:

AL 8697 is a specific and orally active p38_ MAPK inhibitor (IC50: 6 nM), 14-fold less potent in p38_ MAPK (IC50: 82 nM). It exhibits anti-inflammatory activity.

CAS nr:

1057394-06-5

Purity:

98%

Molecular Weight:

402,41

SMILES:

O=C(NC1CC1)C2=CC(F)=C(C)C(C3=C(F)C4=NN=C(C(C)(C)C)N4C=C3F)=C2

Formula:

C21H21F3N4O

Pathway:

MAPK

Target:

p38 MAPK