Bioactivity:

PF-0463481 succinate is a potent and orally active dual antagonist of CCR2/CCR5 with comparable human and rodent CCR2 potency with IC50 of 20.8 nM.

CAS nr:

2140301-98-8

Purity:

98%

Molecular Weight:

629,67

SMILES:

O=C(N1[C@@]2([H])C[C@@]([H])(C1)N(C3=NC=NC(C(F)(F)F)=C3)C2)[C@@]4(C[C@@H](CC4)N[C@@H]5[C@@H](COCC5)OC)C(C)C.OC(CCC(O)=O)=O

Formula:

C29H42F3N5O7

Pathway:

Neuroscience,Immunology/Inflammation

Target:

COX,COX