Bioactivity:

PKF050-638 inhibits the CRM1-mediated Rev nuclear export by disrupting CRM1-NES interaction. PKF050-638 is an effective and selective inhibitor of HIV-1 Rev (IC50=0.04 _M).

CAS nr:

528893-52-9

Purity:

98%

Molecular Weight:

292,72

SMILES:

O=C(OCC)/C=C\N1N=CN=C1C2=CC(Cl)=CC=C2N

Formula:

C13H13ClN4O2

Pathway:

Proteases/Proteasome,Microbiology/Virology

Target:

HIV Protease,HIV Protease