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Bioactivity:
PNU 112455A is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 _M, respectively.
CAS nr:
21886-12-4
Purity:
98%
Molecular Weight:
301,75
SMILES:
Cl.Nc1cc(Nc2ccc(cc2)S(N)(=O)=O)ncn1
Formula:
C10H12ClN5O2S
Pathway:
Cell Cycle/Checkpoint
Target:
CDK