Bioactivity:

TC-I 2014 shows antiallodynic properties in pain models. TC-I 2014 is a potent and orally active Benzimidazole-containing transient receptor potential melastatin 8 antagonist (IC50: 0.8 nM, 3.0 nM, and 4.4 nM for canine, human and rat channels respectivel

CAS nr:

1221349-53-6

Purity:

98%

Molecular Weight:

467,41

SMILES:

FC(C1=CC=CC=C1C2=CC(C(F)(F)F)=C3C(N=C(C4=NOC5(CCCCC5)C4)N3)=C2)(F)F

Formula:

C23H19F6N3O

Pathway:

Membrane transporter/Ion channel

Target:

TRP/TRPV Channel