Bioactivity:

J-104132 is a potetn and selective endothelin A/B receptor antagonist (Ki: cloned human ETA = 0.034 nM; cloned human ETB = 0.104 nM) . In vitro, J-104132 is a potent antagonist of ET-1-induced accumulation of [3H]inositol phosphates in Chinese hamster ova

CAS nr:

198279-45-7

Purity:

98%

Molecular Weight:

531,61

SMILES:

O=C([C@@H]1[C@@H](C2=CC=C(OCO3)C3=C2)C4=CC=C(CCCC)N=C4[C@H]1C5=CC=C(OC)C=C5C[C@@H](C(O)=O)C)O

Formula:

C31H33NO7

Pathway:

Target: