Bioactivity:

Tetrahydroxystilbene-2-O-_-D-glucoside is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-_-D-glucoside induces expression of erythropoietin, PPAR-_ coactivator 1_ (PGC-1_) and haemoglobin in astrocytes and PC12 neuronal-like cells. In vivo, Tetrahydroxystilbene-2-O-_-D-glucoside treatment restores memory impairment, as assessed by the passive avoidance test, in SD, A_ and KA mouse models. In the hippocampus of mice given Tetrahydroxystilbene-2-O-_-D-glucoside in their diet, levels of erythropoietin, PGC-1_ and haemoglobin were increased. Treatment with Tetrahydroxystilbene-2-O-_-D-glucoside might be a therapeutic strategy for memory impairment in neurodegenerative disease, physiological ageing or traumatic brain injury.

CAS nr:

55327-45-2

Purity:

98%

Molecular Weight:

406,38

SMILES:

OC[C@H]1O[C@H]([C@@H]([C@H]([C@@H]1O)O)O)Oc2c(C=Cc3ccc(O)cc3)cc(O)cc2O

Formula:

C20H22O9

Pathway:

Others

Target:

Others