Bioactivity:

INU-152 is a pan-RAF inhibitor. INU-152 has potent anti-tumor activity in preclinical models of BRAFV600E mutant cancer. INU-152 inhibits all RAF isoforms and inhibits MAPK pathways in mutant BRAF cells. INU-152 exhibits minimal paradoxical pathway activa

CAS nr:

1380228-30-7

Purity:

98%

Molecular Weight:

469,43

SMILES:

FC1=C(NS(C2=COC=C2)(=O)=O)C=CC(F)=C1NC3=C(C4=NC=NC5=C4N=CN5)C=CC=N3

Formula:

C20H13F2N7O3S

Pathway:

Target: