Bioactivity:

PF-06250112 is an effective and highly selective BTK inhibitor (IC50: 0.5 nM. PF-06250112 displays an inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC (IC50s: 0.9 nM and 1.2 nM, respectively).

CAS nr:

1609465-89-5

Purity:

98%

Molecular Weight:

438,43

SMILES:

O=C(N)C1=C(N(N=C1C2=CC=C(C=C2)OC3=CC=C(C=C3F)F)[C@@H]4CN(CCC4)C#N)N

Formula:

C22H20F2N6O2

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

BTK,BTK