Bioactivity:

PROTAC ER_ Degrader-2 comprises a cIAP1 ligand binding group, a linker and an estrogen receptor _ (ER_) binding group. PROTAC ER_ Degrader-2 is an ER_ degrader. Maximal ER_ degradation at 30 _M concentration in human mammary tumor MCF7 cells. Degradation

CAS nr:

1351169-29-3

Purity:

98%

Molecular Weight:

763,96

SMILES:

C[C@@]12[C@](CC/C2=N\OCC(NCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@H](N)CC3=CC=CC=C3)=O)=O)=O)([H])[C@@]4([H])[C@](C5=CC=C(O)C=C5CC4)([H])CC1

Formula:

C42H61N5O8

Pathway:

Others

Target:

Others