Bioactivity:

PF-543 inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.

CAS nr:

1706522-79-3

Purity:

98%

Molecular Weight:

502,1

SMILES:

OC[C@@H]1N(CC2=CC=C(COC3=CC(CS(=O)(C4=CC=CC=C4)=O)=CC(C)=C3)C=C2)CCC1.[H]Cl

Formula:

C27H32ClNO4S

Pathway:

GPCR/G Protein,GPCR/G Protein,Apoptosis,Autophagy

Target:

LPL Receptor,S1P Receptor,Apoptosis,Autophagy