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Bioactivity:
SSR128129E is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 _M), but not affecting other related RTKs.
CAS nr:
848318-25-2
Purity:
98%
Molecular Weight:
346,31
SMILES:
Cc1c(n2ccccc2c1OC)C(=O)c1cc(c(cc1)N)C(=O)[O-].[Na+]
Formula:
C18H15N2O4�Na
Pathway:
Angiogenesis,Tyrosine Kinase/Adaptors
Target:
FGFR,FGFR