Bioactivity:

MBM-17S effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM-17S shows antitumor activities, and no obvious toxicity to mice.MBM-17S is a potent NIMA-related kinase 2 (Nek2) inhibitor, with an IC50 of 3 n

CAS nr:

2083621-91-2

Purity:

98%

Molecular Weight:

716,74

SMILES:

O=C(O)CCC(O)=O.O=C(O)CCC(O)=O.NC(C(C=C1)=C(OCC2=CC=CC=C2)C=C1C3=CN=C4N3C=CC(C5=CN(CCN(C)C)N=C5)=C4)=O

Formula:

C36H40N6O10

Pathway:

Chromatin/Epigenetic,Cell Cycle/Checkpoint

Target:

Aurora Kinase,Aurora Kinase