Bioactivity:

Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate cancer cell growth through activation of cell apoptosis and downregulation of androgen receptor ex

CAS nr:

23027-91-0

Purity:

98%

Molecular Weight:

526,5

SMILES:

C[C@@]12OC(=O)[C@@]3(O)CC[C@H]4C([C@H](O)C=C5CC=CC(=O)[C@]45C)[C@@]4(O)O[C@@]13[C@@H](C4=O)[C@]1(C)C[C@H]2OC(=O)C1=C

Formula:

C28H30O10

Pathway:

MAPK,Immunology/Inflammation,JAK/STAT signaling,Chromatin/Epigenetic,Stem Cells,JAK/STAT signaling,Stem Cells,Angiogenesis,MAPK,Endocrinology/Hormones,NF-_b,Apoptosis,MAPK,Autophagy,Apoptosis

Target:

ERK,ROS,JAK,JAK,STAT,STAT,JAK,JAK,JNK,Androgen Receptor,NF-_B,BCL,p38 MAPK,Autophagy,p53