Bioactivity:

ZM 39923 HCl is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.

CAS nr:

1021868-92-7

Purity:

98%

Molecular Weight:

367,91

SMILES:

Cl.CC(C)N(CCC(=O)C1=CC=C2C=CC=CC2=C1)CC1=CC=CC=C1

Formula:

C23H25NO�HCl

Pathway:

Stem Cells,Angiogenesis,JAK/STAT signaling,Chromatin/Epigenetic,Others,Angiogenesis,JAK/STAT signaling,Tyrosine Kinase/Adaptors

Target:

JAK,JAK,JAK,JAK,Others,EGFR,EGFR,EGFR