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Bioactivity:
PLX5622 hemifumarate is a highly selective brain penetrant and oral active inhibitor of CSF1R(Ki of 5.9 nM).
CAS nr:
T12505
Purity:
98%
Molecular Weight:
453,45
SMILES:
COC1=NC=C(F)C=C1CNC2=NC(F)=C(CC3=CNC4=NC=C(C)C=C43)C=C2.O=C(O)/C=C/C(O)=O.[1/2]
Formula:
C23H21F2N5O3
Pathway:
Tyrosine Kinase/Adaptors
Target:
c-Fms