Bioactivity:

JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 _M). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endo

CAS nr:

942655-44-9

Purity:

98%

Molecular Weight:

323,35

SMILES:

COc1c(cc(cc1)C(=O)Nc1n[nH]c(c1)c1ccccc1)OC

Formula:

C18H17N3O3

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis

Target:

VEGFR,VEGFR