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Bioactivity:
CCT245737 is an orally active and selective Chk1 inhibitor (IC50: 1.3 nM); CCT245737 shows much less activity against Chk2 (IC50: 2440 nM).
CAS nr:
1489389-18-5
Purity:
98%
Molecular Weight:
379,34
SMILES:
FC(F)(F)c1cnc(Nc2cnc(cn2)C#N)cc1NC[C@H]1CNCCO1
Formula:
C16H16F3N7O
Pathway:
Cell Cycle/Checkpoint
Target:
Chk