Bioactivity:

(S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM. (S,R,S)-AHPC-Me h

CAS nr:

1948273-03-7

Purity:

98%

Molecular Weight:

481,05

SMILES:

Cl.C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](N)C(C)(C)C)c1ccc(cc1)-c1scnc1C

Formula:

C23H33ClN4O3S

Pathway:

Others

Target:

Others