Bioactivity:

PF06650833 is an effective, selective and orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) (IC50s: 0.2 and 2.4 nM in the cell and PBMC assay).

CAS nr:

1817626-54-2

Purity:

98%

Molecular Weight:

361,37

SMILES:

CC[C@H]1[C@H](NC(=O)[C@H]1F)COC2=NC=CC3=CC(=C(C=C32)OC)C(=O)N

Formula:

C18H20FN3O4

Pathway:

NF-_b,Immunology/Inflammation

Target:

IRAK,IRAK