KenPaullone T2247
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Kenpaullone, a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation. Kenpaullone promotes iTreg cell differentiation through increased and prolonged transcription of foxp3 gene by enhancing TGF_-Smad3 signaling pathway.
CAS nr:
142273-20-9
Purity:
98%
Molecular Weight:
327,18
SMILES:
c12ccccc1NC(=O)Cc1c2[nH]c2c1cc(cc2)Br
Formula:
C16H11BrN2O
Pathway:
Cell Cycle/Checkpoint,Stem Cells,PI3K/Akt/mTOR signaling
Target:
CDK,GSK-3,GSK-3
