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Bioactivity:
WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.
CAS nr:
1213269-23-8
Purity:
98%
Molecular Weight:
494,18
SMILES:
COc1c(Nc2ncc(Cl)c(Oc3cc(NC(=O)C=C)ccc3)n2)ccc(c1)N1CCN(C)CC1
Formula:
C25H27ClN6O3
Pathway:
Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling
Target:
EGFR,EGFR,EGFR