Bioactivity:

DHODH-IN-3 is an effective inhibitor of human dihydroorotate dehydrogenase (HsDHODH) with IC50 value of 261 nM. DHODH-IN-3 binds to the ubiquinone binding cavity in DHODH with a Kiapp of 32 nM. DHODH-IN-3 has the potential to treat malaria.

CAS nr:

1148126-04-8

Purity:

98%

Molecular Weight:

312,75

SMILES:

C/C(O)=C(C#N)/C(NC1=CC=C(C2=CC=CC=C2)C=C1Cl)=O

Formula:

C17H13ClN2O2

Pathway:

Others

Target:

Others