Bioactivity:

GW806742X is an inhibitor of Mixed Lineage Kinase Domain-Like protein (MLKL) which binds the MLKL pseudokinase domain (Kd: 9.3 _M) with anti-necroptosis activity.�GW806742X has activity against VEGFR2.

CAS nr:

579515-63-2

Purity:

98%

Molecular Weight:

573,55

SMILES:

O=S(C1=CC=CC(NC2=NC=CC(N(C)C3=CC=C(NC(NC4=CC=C(OC(F)(F)F)C=C4)=O)C=C3)=N2)=C1)(N)=O

Formula:

C25H22F3N7O4S

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,MAPK

Target:

VEGFR,VEGFR,MLK