Bioactivity:

Maraviroc is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1_(IC50=3.3 nM), MIP-1_ (IC50=7.2 nM) and RANTES(IC50=5.2 nM).Maraviroc inhibits HIV-1 entry via CCR5 coreceptor interaction.

CAS nr:

376348-65-1

Purity:

98%

Molecular Weight:

513,67

SMILES:

CC(C)c1nnc(C)n1[C@H]1C[C@@H]2CC[C@H](C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccccc1

Formula:

C29H41F2N5O

Pathway:

Microbiology/Virology,Immunology/Inflammation,Proteases/Proteasome,Microbiology/Virology

Target:

CCR,CCR,HIV Protease,HIV Protease