Bioactivity:

CU CPT 4a is a selective TLR3 inhibitor (IC50: 3.44 _M in RAW 264.7 cells). It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-_ and IL-1_ in whole cells.

CAS nr:

1279713-77-7

Purity:

98%

Molecular Weight:

377,82

SMILES:

O=C(O)[C@@H](CC1=CC=CC=C1)NC(C2=C(Cl)C3=CC=C(F)C=C3S2)=O

Formula:

C18H13ClFNO3S

Pathway:

Immunology/Inflammation

Target:

TLR