Bioactivity:

Calhex 231 hydrochloride is a CaSR inhibitor with the potential for diabetic cardiomyopathy treatment. It blocks Ca2+-induced accumulation of [3H]inositol phosphate (IC50: 0.39 _M in HEK293 cells).

CAS nr:

2387505-78-2

Purity:

98%

Molecular Weight:

443,41

SMILES:

O=C(N[C@@H]1[C@@H](N[C@@H](C2=C3C=CC=CC3=CC=C2)C)CCCC1)C4=CC=C(Cl)C=C4.[H]Cl

Formula:

C25H28Cl2N2O

Pathway:

GPCR/G Protein

Target:

CaSR