Bioactivity:

FK706 is a slow-binding and competitive human neutrophil elastase inhibitor (IC50: 83 nM; Ki: 4.2 nM). FK706 also inhibits mouse neutrophil elastase and porcine pancreatic elastase (IC50s: 22 nM and 100 nM, respectively). FK706 has an anti-inflammatory ef

CAS nr:

144055-55-0

Purity:

98%

Molecular Weight:

592,54

SMILES:

O=C(NC(C(C)C)C(C(F)(F)F)=O)[C@H]1N(C([C@H](C(C)C)NC(C2=CC=C(C(NCC(O[Na])=O)=O)C=C2)=O)=O)CCC1

Formula:

C26H32F3N4NaO7

Pathway:

Proteases/Proteasome

Target:

Serine Protease