Bioactivity:

AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 _M, respectively[1]. AZ PFKFB3 26 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 23 nM.

CAS nr:

1704740-52-2

Purity:

98%

Molecular Weight:

402,49

SMILES:

O=C([C@H]1NCCC1)NC2=CC=C(OC3=CC4=C(N(CC(C)C)C=C4C#N)C=C3)C=C2

Formula:

C24H26N4O2

Pathway:

Metabolism

Target:

Glucokinase