Ro5-3335 T4687
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Ro 5-3335 is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins (IC50 = 1.1 _M). It represses RUNX1/CBF_-dependent transactivation in reporter assays and inhibits transcriptional regulation by RUNX
CAS nr:
30195-30-3
Purity:
98%
Molecular Weight:
259,69
SMILES:
Clc1ccc2NC(=O)CN=C(c3ccc[nH]3)c2c1
Formula:
C13H10ClN3O
Pathway:
DNA Damage/DNA Repair,Cell Cycle/Checkpoint
Target:
DNA/RNA Synthesis,DNA/RNA Synthesis
