Bioactivity:

PF-249 is a beta1-selective AMPK agonist and is a potent AMPK activator. PF-249 showed robust activation of AMPK in rat kidneys as well as desirable oral absorption, low plasma clearance, and negligible renal clearance in preclinical species.

CAS nr:

1467059-70-6

Purity:

98%

Molecular Weight:

345,78

SMILES:

O=C(C1=CNC2=C1C=C(C3=CC=C(N(C)C)N=C3OC)C(Cl)=C2)O

Formula:

C17H16ClN3O3

Pathway:

Target: