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Bioactivity:
Dabrafenib is a selective inhibitor of mutated forms of BRAF kinase (IC50s: 0.7/5 nM for B-Raf (V600E)/C-Raf).
CAS nr:
1195765-45-7
Purity:
98%
Molecular Weight:
519,56
SMILES:
CC(C)(C)c1nc(c(s1)-c1ccnc(N)n1)-c1cccc(NS(=O)(=O)c2c(F)cccc2F)c1F
Formula:
C23H20F3N5O2S2
Pathway:
MAPK
Target:
Raf