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Bioactivity:
VE-821 is a selective ATP competitive inhibitor of ATR( Ki/IC50: 13/26 nM in cell-free assays).
CAS nr:
1232410-49-9
Purity:
98%
Molecular Weight:
368,41
SMILES:
CS(=O)(=O)c1ccc(cc1)-c1cnc(N)c(n1)C(=O)Nc1ccccc1
Formula:
C18H16N4O3S
Pathway:
PI3K/Akt/mTOR signaling,DNA Damage/DNA Repair
Target:
ATM/ATR,ATM/ATR