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Bioactivity:
PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binding simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site.
CAS nr:
391210-00-7
Purity:
98%
Molecular Weight:
561,09
SMILES:
c1cc(c(cc1I)F)Nc1c(c(c(cc1C(=O)NOCC(CO)O)Br)F)F
Formula:
C16H13BrF3IN2O4
Pathway:
MAPK
Target:
MEK