Bioactivity:

Trifluridine is a fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This

CAS nr:

70-00-8

Purity:

98%

Molecular Weight:

296,2

SMILES:

[C@@H]1(n2cc(c(=O)[nH]c2=O)C(F)(F)F)O[C@@H]([C@H](C1)O)CO

Formula:

C10H11F3N2O5

Pathway:

Cell Cycle/Checkpoint,DNA Damage/DNA Repair,Cell Cycle/Checkpoint,Microbiology/Virology,DNA Damage/DNA Repair

Target:

Nucleoside Antimetabolite/Analog,Nucleoside Antimetabolite/Analog,DNA/RNA Synthesis,HSV,DNA/RNA Synthesis