Bioactivity:

EZ-482 is a novel ligand of apolipoprotein (apoE). EZ-482 binds to apoE4 by a unique N-terminal allosteric effect and it also binds to sites on apoE in the C-terminal domain (Kds: 5-10 _M for apoE3 and apoE4).

CAS nr:

1016456-76-0

Purity:

98%

Molecular Weight:

498,94

SMILES:

O=C(NC1=CC(S(=O)(NC2=CC=CC(Cl)=C2)=O)=CC=C1O)CC3=NN(C)C(C4=C3C=CC=C4)=O

Formula:

C23H19ClN4O5S

Pathway:

Others

Target:

Others