Bioactivity:

A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 _M, respectively; more than 100-fold selective over other histone methyltransferases and non-epigenetic targets.

CAS nr:

1982372-88-2

Purity:

98%

Molecular Weight:

359,25

SMILES:

Clc1cc3c(cc1Cl)c(nnc3NC2CCCC2)c4ccncc4

Formula:

C18H16Cl2N4

Pathway:

Chromatin/Epigenetic

Target:

Histone Methyltransferase