Bioactivity:

PF-06372865 is a high-affinity ligand at GABAA receptors containing _1/_2/_3/_5 subunits (Kis: 2.9 nM, 21 nM, 134 nM for _2, _1 PAM, _2 PAM, respectively). It also has a low affinity for _4/_6 subunits. PF-06372865 is an orally active and _2/_3/_5 subtype

CAS nr:

1614245-70-3

Purity:

98%

Molecular Weight:

440,49

SMILES:

CCN1C2=NN=CC(C(C=C3)=CC(C(C=CC([S](CC)(=O)=O)=C4)=C4OC)=C3F)=C2N=C1

Formula:

C22H21FN4O3S

Pathway:

Others

Target:

Others