Rilzabrutinib T12542
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Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
PRN1008 is a reversible covalent, selective and oral active inhibitor of Bruton�s Tyrosine Kinase (BTK)(IC50 of 1.3 nM).
CAS nr:
1575596-29-0
Purity:
98%
Molecular Weight:
665,76
SMILES:
CC(C)(\C=C(/C#N)C(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc12)N1CCN(CC1)C1COC1
Formula:
C36H40FN9O3
Pathway:
Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling,Angiogenesis,Tyrosine Kinase/Adaptors,Others,Angiogenesis,JAK/STAT signaling,Tyrosine Kinase/Adaptors
Target:
HER,HER,HER,BTK,BTK,Others,EGFR,EGFR,EGFR