Bioactivity:

VU0529331 is a modestly selective non-GIRK1-containing G protein-gated, inwardly-rectifying, potassium channel activator (EC50s: 5.1 ﾵM and 5.2 ﾵM for GIRK2 and GIRK1/2 in HEK293 cells, respectively). It is also effective on the GIRK4 homomeric channel.

CAS nr:

1286725-49-2

Purity:

98%

Molecular Weight:

384,43

SMILES:

O=C(C1=NC=CN=C1)N2CC3=C(N4C=CC=C4)N(C5=CC(C)=C(C)C=C5)N=C3C2

Formula:

C22H20N6O

Pathway:

Others

Target:

Others