Bioactivity:

AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.

CAS nr:

1384071-99-1

Purity:

98%

Molecular Weight:

473,44

SMILES:

CC(C)N1C2=C(C(=N1)C3=CC=C(C=C3)NC(=O)NC4=C(C=CC(=C4)C(F)(F)F)F)C(=NC=N2)N

Formula:

C22H19F4N7O

Pathway:

MAPK,Tyrosine Kinase/Adaptors,Apoptosis,Tyrosine Kinase/Adaptors,Angiogenesis,MAPK,PI3K/Akt/mTOR signaling

Target:

Raf,c-RET,c-RET,Src,Src,S6 Kinase,S6 Kinase