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Bioactivity:
CHZ868 is a type II JAK2 inhibitor (IC50: 0.17 _M in EPOR JAK2 WT Ba/F3 cell).
CAS nr:
1895895-38-1
Purity:
98%
Molecular Weight:
423,42
SMILES:
CC(NC1=CC(OC2=CC=C(N(C)C(NC3=CC=C(F)C=C3F)=N4)C4=C2C)=CC=N1)=O
Formula:
C22H19F2N5O2
Pathway:
Stem Cells,Angiogenesis,JAK/STAT signaling,Chromatin/Epigenetic
Target:
JAK,JAK,JAK,JAK