Bioactivity:

TRAF-STOP inhibitor 6877002, is a selective inhibitor of CD40-TRAF6 interaction. TRAF-STOP 6877002 reduces leukocyte recruitment, and reduces macrophage activation; reduces macrophage proliferation in atherosclerotic plaques.

CAS nr:

433249-94-6

Purity:

98%

Molecular Weight:

251,32

SMILES:

O=C(C1=CC=CC=C1)/C=C/NC2=C(C=CC(C)=C2)C

Formula:

C17H17NO

Pathway:

NF-_b

Target:

NF-_B