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Bioactivity:
PF-06445974 has good selectivity for PDE4D, excellent brain permeability, and has a high level of specific binding in the "cold tracer" study.
CAS nr:
2055776-17-3
Purity:
98%
Molecular Weight:
346,37
SMILES:
N#CC1=CC=C(C(C2=NC=CC=C23)=C(N3CCN4C5CC5)C4=O)C=C1F
Formula:
C20H15FN4O
Pathway:
Target: