Bioactivity:

VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 _M for caspase-like proteasomes.

CAS nr:

1624602-30-7

Purity:

98%

Molecular Weight:

477,88

SMILES:

C1CN(CCN1c1c2ccc(cc2ncc1)Cl)S(=O)(=O)c1c(cc(cc1)[N+](=O)[O-])[N+](=O)[O-]

Formula:

C19H16ClN5O6S

Pathway:

Proteases/Proteasome,Apoptosis,Proteases/Proteasome,Ubiquitination,Apoptosis

Target:

Caspase,Caspase,Proteasome,Proteasome,Apoptosis