Bioactivity:

AZD9567 (compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. It shows excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1].

CAS nr:

1893415-00-3

Purity:

98%

Molecular Weight:

494,53

SMILES:

CC(F)(F)C(N[C@H]([C@H](OC1=CC2=C(N(C(C=C3)=CN(C)C3=O)N=C2)C=C1)C4=CC=CC=C4)C(C)C)=O

Formula:

C27H28F2N4O3

Pathway:

Target: