Bioactivity:

AS1810722 is an orally active and potent STAT6 inhibitor(IC50 :1.9 nM). AS1810722 shows a good profile of CYP3A4 inhibition. AS1810722, a derivative of fused bicyclic pyrimidine, has the potential for allergic diseases such as asthma and atopic diseases r

CAS nr:

909561-15-5

Purity:

98%

Molecular Weight:

477,52

SMILES:

O=C(N)CN1CCN(C2=CC=C(NC3=NC=C4C(N(CC5=CC(F)=CC(F)=C5)C=C4)=N3)C=C2)CC1

Formula:

C25H25F2N7O

Pathway:

Metabolism,Stem Cells,JAK/STAT signaling

Target:

P450,STAT,STAT