Bioactivity:

Celastrol is an effective proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome(IC50=2.5 _M) with antioxidant and anti-inflammatory activity.

CAS nr:

34157-83-0

Purity:

98%

Molecular Weight:

450,62

SMILES:

CC1=C(O)C(=O)C=C2C1=CC=C1[C@@]2(C)CC[C@@]2(C)[C@@H]3C[C@@](C)(CC[C@]3(C)CC[C@]12C)C(O)=O

Formula:

C29H38O4

Pathway:

Proteases/Proteasome,Ubiquitination,Autophagy,Apoptosis,Autophagy

Target:

Proteasome,Proteasome,Autophagy,Apoptosis,Mitophagy